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ベンゾジアゼピンの依存性特性のニューラルベースは,ベンゾジアゼピンの依存性特性のニューラルベースです

Kelly R Tan1, Matthew Brown, Gwenaël Labouèbe

  • 1Department of Basic Neurosciences, Medical Faculty, University of Geneva, CH-1211 Geneva, Switzerland.

Nature
|February 12, 2010
PubMed
まとめ

ベンゾジアゼピンは,GABA (A) 受容体を調節することにより,ドーパミンニューロン活動を強化し,中毒を引き起こす. アルファ1を含有する受容体をターゲットにすることで,中毒のない薬が作れる.

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