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Updated: Jun 16, 2026

Detecting Somatic Genetic Alterations in Tumor Specimens by Exon Capture and Massively Parallel Sequencing
11:02

Detecting Somatic Genetic Alterations in Tumor Specimens by Exon Capture and Massively Parallel Sequencing

Published on: October 18, 2013

癌ゲノムにおける変異と選択のシグネチャー

Graham R Bignell1, Chris D Greenman, Helen Davies

  • 1Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.

Nature
|February 19, 2010
PubMed
まとめ

研究者らは,がん細胞系における数千の同同位体の欠損を特定し,がんゲノム進化の洞察を明らかにした. これらの発見は,がんの発症におけるDNA破裂と選択圧力の違いを区別するのに役立ちます.

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