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Updated: Jun 16, 2026

Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles
11:45

Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles

Published on: August 22, 2018

角的に置換された1-アザビサイクルリングシステムのエナチオセレクティブ合成: aza-Copeの再配置を用いた動的運動解像度

Tatsuya Ito1, Larry E Overman, Jocelyn Wang

  • 1Department of Chemistry, University of California, Irvine, 1102 Natural Sciences II, Irvine, California 92697-2025, USA.

Journal of the American Chemical Society
|February 24, 2010
PubMed
まとめ

新しいエナチオセレクティブ合成により,高収量で99%のエナチオメリック過剰 (ee) を有する,角的に置換された1-アザビサイクリックアミンが得られます. この方法は,効率的なステレオ選択合成のためのユニークなダイナミック・キネティック解像度戦略を使用しています.

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[3,3] Sigmatropic Rearrangement of 1,5-Dienes: Cope Rearrangement

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