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Updated: Jun 15, 2026

Chemoselective Modification of Viral Surfaces via Bioorthogonal Click Chemistry
12:31

Chemoselective Modification of Viral Surfaces via Bioorthogonal Click Chemistry

Published on: August 19, 2012

素早く合成されるバイアリラザサイクロオクティノノンの素早いCuフリークリック化学

John C Jewett1, Ellen M Sletten, Carolyn R Bertozzi

  • 1Department of Chemistry and Howard Hughes Medical Institute, University of California, Berkeley, California 94720, USA.

Journal of the American Chemical Society
|March 2, 2010
PubMed
まとめ

バイオオートゴーナル化学は,新しい生物学的研究を可能にします. 新型バイアリラザサイクロオクティノーン (BARAC) 試薬により,アジドでラベルを貼ったグリカンの生細胞イメージングが効率的に可能になり,信号からノイズの変換が高く,in vivoアプリケーションに役立ちます.

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Cycloaddition Reactions: Overview

Cycloadditions are one of the most valuable and effective synthesis routes to form cyclic compounds. These are concerted pericyclic reactions between two unsaturated compounds resulting in a cyclic product with two new σ bonds formed at the expense of π bonds. The [4 + 2] cycloaddition, known as the Diels–Alder reaction, is the most common. The other example is a [2 + 2] cycloaddition.
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Cycloaddition Reactions: MO Requirements for Photochemical Activation

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