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Updated: Jun 15, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
10:17

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

ヴィンドロリン全合成の非対称性

Daisuke Kato1, Yoshikazu Sasaki, Dale L Boger

  • 1Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.

Journal of the American Chemical Society
|March 2, 2010
PubMed
まとめ

この研究では,タンデムサイクロアディションカスケードを使用して, (-) - ヴィンドロリンの簡潔な非対称的全合成を詳細に説明しています. キラル置換剤はステレオ化学を制御し,ペンタサイクリックコアとその機能を1つのステップで効率的に構築します.

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