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Updated: Jun 15, 2026

Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model
03:45

Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model

Published on: August 8, 2022

タンパク質集積物と新型プレシニリン遺伝子変異は,イディオパシー拡張心筋病のイディオパシー拡張心筋病の遺伝子変異である

Davide Gianni1, Airong Li, Giuseppina Tesco

  • 1Cardiovascular Institute, Beth Israel Deaconess Medical Center, Boston, MA 02125, USA.

Circulation
|March 3, 2010
PubMed
まとめ

Idiopathic dilated cardiomyopathy (iDCM) は,認知症に類似して,心臓細胞における異常なタンパク質の蓄積に起因する可能性があります. この集積は,カルシウム処理とプレセニリン-1 (PSEN1) 遺伝子発現に影響を与え,心臓機能に影響を与えます.

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Enrichment of Detergent-insoluble Protein Aggregates from Human Postmortem Brain

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