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Updated: Jun 15, 2026

Analytical Techniques for Assaying Nitric Oxide Bioactivity
11:28

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Published on: June 18, 2012

窒素性ストレス下におけるサイクロオキシゲネーゼ不活性化を防ぐための基板結合の物理的証拠

Ruba S Deeb1, Cynthia Cheung, Tal Nuriel

  • 1Department of Pathology, Weill Cornell Medical College of Cornell University, 1300 York Avenue, New York, New York 10065, USA. rsdeeb@med.cornell.edu

Journal of the American Chemical Society
|March 4, 2010
PubMed
まとめ

基板への結合は,サイクルオキシゲネーゼ-1 (COX-1) を反応性窒素種による無活性化から保護する. この発見は,酸化ストレス中のCOX-1活性に対する新しい保護機構を明らかにしています.

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