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Updated: Jun 15, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
10:17

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

C,N-サイクリックアゾメチンイミンとアルファ,ベータ不飽和アルデヒドの触媒エナチオセレクティブ1,3-二極サイクロアディション

Takuya Hashimoto1, Yuko Maeda, Masato Omote

  • 1Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502, Japan.

Journal of the American Chemical Society
|March 5, 2010
PubMed
まとめ

この研究では,エナチオセレクティブの1,3-二極サイクロアディション反応のためのC,N-サイクルアゾメチンイミンを導入しています. これらの反応は,テトラヒドロアイソキノリンやピペリジンなどの価値ある医薬品の構成要素を効率的に生成します.

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