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Updated: Jun 15, 2026

Quantifying Tissue-Specific Proteostatic Decline in Caenorhabditis elegans
09:18

Quantifying Tissue-Specific Proteostatic Decline in Caenorhabditis elegans

Published on: September 7, 2021

セストリンは,TORのフィードバック阻害剤として,年齢関連の病理を予防します

Jun Hee Lee1, Andrei V Budanov, Eek Joong Park

  • 1Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, School of Medicine, University of California San Diego (UCSD), La Jolla, CA 92093-0723, USA.

Science (New York, N.Y.)
|March 6, 2010
PubMed
まとめ

セストリンは,細胞がストレスに反応するのを助けるタンパク質です. ドロソフィラ・セストリン (dSesn) の喪失は,年齢関連の疾患を引き起こしたが,AMPKを活性化したり,TORを抑制したりすることで,これらの問題を防ぐことができた.

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Isolation of Intermediate Filament Proteins from Multiple Mouse Tissues to Study Aging-associated Post-translational Modifications09:29

Isolation of Intermediate Filament Proteins from Multiple Mouse Tissues to Study Aging-associated Post-translational Modifications

Published on: May 18, 2017

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