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Updated: Jun 15, 2026

A Protocol for Using Förster Resonance Energy Transfer (FRET)-force Biosensors to Measure Mechanical Forces across the Nuclear LINC Complex
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受容体運動の制限は細胞の反応を変化させる:EphA2による物理的力感知

Khalid Salaita1, Pradeep M Nair, Rebecca S Petit

  • 1Howard Hughes Medical Institute, Department of Chemistry, University of California, Berkeley, CA 94720, USA.

Science (New York, N.Y.)
|March 13, 2010
PubMed
まとめ

EphA2受容体のチロシンキナーゼシグナル伝達は,発育と癌において極めて重要であり,物理的な細胞相互作用によって調節されます. EphA2受容体の動きを操作すると,乳がんにおける細胞反応と侵入の可能性が変化する.

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