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ウィスコット・オルドリッヒ症候群では発現が欠陥のあるCD43分子によるT細胞活性化の強化

J K Park1, Y J Rosenstein, E Remold-O'Donnell

  • 1Division of Pediatric Oncology, Dana Farber Cancer Institute, Boston, Massachusetts.

Nature
|April 25, 1991
PubMed
まとめ

CD43はT細胞の活性化を促進し,その機能は細胞内領域に依存する. この分子は免疫反応において重要な役割を果たしており,その欠陥はウィスコット・オルドリッヒ症候群と関連している.

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