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Updated: May 9, 2026

Measuring TCR-pMHC Binding In Situ using a FRET-based Microscopy Assay
19:05

Measuring TCR-pMHC Binding In Situ using a FRET-based Microscopy Assay

Published on: October 30, 2015

2次元のTCRとpMHCの相互作用の運動学は,T細胞の反応性を決定する

Jun Huang1, Veronika I Zarnitsyna, Baoyu Liu

  • 1Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332, USA.

Nature
|April 2, 2010
PubMed
まとめ

ペプチド-MHC (pMHC) に結合する二次元T細胞受容体 (TCR) は,T細胞の反応性と病原体の差別化に不可欠な急速な運動性と広範な親和性を明らかにします. これらの発見は,以前の3D分析に異議を唱え,細胞環境の役割を強調しています.

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