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Updated: Jun 14, 2026

Expression, Purification, Crystallization, and Enzyme Assays of Fumarylacetoacetate Hydrolase Domain-Containing Proteins
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Expression, Purification, Crystallization, and Enzyme Assays of Fumarylacetoacetate Hydrolase Domain-Containing Proteins

Published on: June 20, 2019

フラボ酵素媒介のアミド水解の触媒

Tathagata Mukherjee1, Yang Zhang, Sameh Abdelwahed

  • 1Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, USA.

Journal of the American Chemical Society
|April 8, 2010
PubMed
まとめ

研究者らは,新しいフラボ酵素Rutaを発見し,E. coliで uracilを酸化することによって,ピリミジン分解経路を開始しました. この発見は,リング開きのためのユニークな酸化機構を明らかにし,フラビン共因子を強調しています.

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