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Updated: Jun 14, 2026

Mouse Naïve CD4+ T Cell Isolation and In vitro Differentiation into T Cell Subsets
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IkappaBzetaは,ROR核受容体との協力により,T(H) 17の開発を規制しています

Kazuo Okamoto1, Yoshiko Iwai, Masatsugu Oh-Hora

  • 1Department of Cell Signaling, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Japan.

Nature
|April 13, 2010
PubMed
まとめ

新しい転写因子であるIkappaBzetaは,インタールイキン17を産生するヘルパーT (T (H)) 17細胞の発達に不可欠です. この発見は,実験的自己免疫脳内炎 (EAE) のような自己免疫疾患に対する新しい治療戦略を提供します.

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