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Updated: Jun 13, 2026

Aptamer-Based Target Detection Facilitated by a 3-Stage G-Quadruplex Isothermal Exponential Amplification Reaction
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Aptamer-Based Target Detection Facilitated by a 3-Stage G-Quadruplex Isothermal Exponential Amplification Reaction

Published on: October 6, 2022

ダイナミック・コンビナトリアル・ライブラリのサイズが,分子認識誘発増幅の検出可能性に与える影響は,

R Frederick Ludlow1, Sijbren Otto

  • 1Centre for Systems Chemistry, Stratingh Institute, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands.

Journal of the American Chemical Society
|April 16, 2010
PubMed
まとめ

より大きなダイナミック・コンビネタリアル・ライブラリ (DCL) は,より優れたバインダーを生成する可能性が高い. シミュレーション結果は,ライブラリサイズを増やすと,強い結合因子とその親和性を検出する確率が高くなり,より大きなDCLが有利であることを示唆しています.

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