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生まれながらのリンパ性細胞は,インターレウキン23依存の生まれながらの腸内病理を駆動する

Sofia Buonocore1, Philip P Ahern, Holm H Uhlig

  • 1Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, UK.

Nature
|April 16, 2010
PubMed
まとめ

インタールエウキン-23 (IL-23) は,先天性免疫細胞,特に先天性リンパ性細胞を駆動して炎症性サイトカインを生成します. これらの細胞を枯渇させると大腸炎を止め,炎症性腸疾患の新たな治療標的を明らかにします.

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