Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

American Trypanosomiasis01:22

American Trypanosomiasis

Chagas disease, or American trypanosomiasis, is a vector-borne parasitic infection caused by Trypanosoma cruzi, a flagellated protozoan (kinetoplastid) of the family Trypanosomatidae. The disease is endemic in Latin America, although cases are increasingly reported worldwide due to human migration. Transmission most commonly occurs when feces of infected triatomine bugs contaminate bite wounds or mucosal surfaces; additional routes include congenital, transfusional, transplant-related, and oral...
Leishmaniasis01:30

Leishmaniasis

Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...
Cholera01:25

Cholera

Cholera is an acute gastrointestinal disease caused by the Gram-negative bacterium Vibrio cholerae. It is transmitted primarily via the fecal-oral route through the ingestion of contaminated water or food.Vibrio cholerae is a motile, Gram-negative bacterium of the family Vibrionaceae, primarily associated with waterborne outbreaks in areas with inadequate sanitation. Although over 200 serogroups of V. cholerae exist, only O1 and O139 are responsible for epidemic cholera. The O1 serogroup,...
Esophageal Achalasia01:27

Esophageal Achalasia

Esophageal achalasia is a chronic neurogenic disorder characterized by impaired relaxation of the lower esophageal sphincter (LES) and absent or ineffective peristalsis in the distal esophagus. This leads to a functional obstruction without a physical blockage, despite significant disruption of esophageal motility.EtiologyAchalasia is caused by degeneration of the myenteric (Auerbach's) plexus, specifically the loss of inhibitory ganglion cells that produce vasoactive intestinal peptide (VIP)...
Toxoplasmosis01:28

Toxoplasmosis

Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...
Giardiasis01:12

Giardiasis

Giardiasis is a globally prevalent intestinal infection caused by the protozoan parasite Giardia duodenalis (also known as G. lamblia or G. intestinalis). This flagellated protozoan is the most frequently identified intestinal parasite in the United States and worldwide. Transmission primarily occurs via the fecal-oral route, with infection arising from ingestion of water or food contaminated with cysts. Individuals in low-resource settings, international travelers, outdoor enthusiasts, daycare...

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

State-of-the-Art Review: Chagas Disease-an Enduring Challenge.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same author

I - Evaluation of Cardiovascular Autonomic Function in Healthy Individuals.

Arquivos brasileiros de cardiologia·2026
Same author

II - Evaluation of Autonomic Control of Heart Rate in Various Clinical Conditions.

Arquivos brasileiros de cardiologia·2026
Same author

Global longitudinal strain as a predictor of outcomes in chronic Chagas´ cardiomyopathy.

PLoS neglected tropical diseases·2025
Same author

Effect of neurohormonal therapeutic in left ventricle global and regional function in Chagas cardiomyopathy in a translational animal experimental model.

Scientific reports·2025
Same author

How Cardiovascular Physical Examination Impacts Clinical Decision-Making in Various Scenarios of Cardiac Valvular Diseases.

Arquivos brasileiros de cardiologia·2025

関連する実験動画

Updated: Jun 13, 2026

In Vitro Drug Screening Against All Life Cycle Stages of Trypanosoma cruzi Using Parasites Expressing β-galactosidase
08:48

In Vitro Drug Screening Against All Life Cycle Stages of Trypanosoma cruzi Using Parasites Expressing β-galactosidase

Published on: November 5, 2021

シャガスの病はシャガスの病です.

Anis Rassi1, Anis Rassi, José Antonio Marin-Neto

  • 1Division of Cardiology, Anis Rassi Hospital, Goiânia, GO, Brazil. arassijr@terra.com.br

Lancet (London, England)
|April 20, 2010
PubMed
まとめ

800万人に感染する寄生虫感染症であるシャガス病は,ベクトル管理と血液スクリーニングにより,制御が改善されています. 早期発見と新しい治療法は,この新興の世界的な健康問題を管理するために不可欠です.

科学分野:

  • トロピカル・メディシン (熱帯医学)
  • 感染症 感染症は感染症です.
  • 寄生虫学とは,寄生虫学である.

背景:

  • シャガス病は,ラテンアメリカに固有のTrypanosoma cruziによって引き起こされる慢性寄生虫感染症で,約800万人の人に感染しています.
  • 感染した人の有意な部分 (30-40%) は,心筋病や消化器系の問題などの重篤な合併症を発症します.
  • 近年,シャガス病の制御に進展がみられるが,非流行地域での出現を含む課題は依然として残っている.

研究 の 目的:

  • シャガス病の管理と制御における最近の進歩をレビューする.
  • 持続的な課題と将来の研究と介入の分野を強調する.

主な方法:

  • 疫学的データと制御プログラムの結果のレビュー.
  • 現在の治療戦略とリスクの階層化モデルの分析.
  • チャガス病管理における新興傾向と満たされていないニーズについての議論.

主要な成果:

  • ベクター制御と献血者のスクリーニングは,シャガス病の発生率と流行を成功裏に減少させました.
  • ベンズニダゾールやニフュルティモックスなどの現在の治療法は有効で,より広い患者グループに推奨されています.
  • 改善されたリスク分層化モデルは,潜在的に疾患の進行を停止したり逆転させたりするための治療をガイドするのに役立ちます.

さらに関連する動画

Sexual Transmission of American Trypanosomes from Males and Females to Naive Mates
13:55

Sexual Transmission of American Trypanosomes from Males and Females to Naive Mates

Published on: January 27, 2019

Demystifying In Vivo Bioluminescence Imaging of a Chagas Disease Mouse Model for Drug Efficacy Studies
07:59

Demystifying In Vivo Bioluminescence Imaging of a Chagas Disease Mouse Model for Drug Efficacy Studies

Published on: May 31, 2024

関連する実験動画

Last Updated: Jun 13, 2026

In Vitro Drug Screening Against All Life Cycle Stages of Trypanosoma cruzi Using Parasites Expressing β-galactosidase
08:48

In Vitro Drug Screening Against All Life Cycle Stages of Trypanosoma cruzi Using Parasites Expressing β-galactosidase

Published on: November 5, 2021

Sexual Transmission of American Trypanosomes from Males and Females to Naive Mates
13:55

Sexual Transmission of American Trypanosomes from Males and Females to Naive Mates

Published on: January 27, 2019

Demystifying In Vivo Bioluminescence Imaging of a Chagas Disease Mouse Model for Drug Efficacy Studies
07:59

Demystifying In Vivo Bioluminescence Imaging of a Chagas Disease Mouse Model for Drug Efficacy Studies

Published on: May 31, 2024

結論:

  • 予防対策は改善されていますが,特に人口の移動により,シャガス病は依然として重要な公衆衛生上の懸念となっています.
  • 症状のない症例の早期発見と治療は十分に活用されていない.
  • 新しい治療法を評価し,シャガス病の世界的な蔓延に対処するためにさらなる研究が必要です.