シャガスの病はシャガスの病です
Anis Rassi1, Anis Rassi, José Antonio Marin-Neto
1Division of Cardiology, Anis Rassi Hospital, Goiânia, GO, Brazil. arassijr@terra.com.br
Lancet (London, England)
|April 20, 2010
まとめ
800万人に感染する寄生虫感染症であるシャガス病は,ベクトル管理と血液スクリーニングにより,制御が改善されています. 早期発見と新しい治療法は,この新興の世界的な健康問題を管理するために不可欠です.
科学分野:
- トロピカル・メディシン (熱帯医学)
- 感染症 感染症は感染症です.
- 寄生虫学とは,寄生虫学である.
背景:
- シャガス病は,ラテンアメリカに固有のTrypanosoma cruziによって引き起こされる慢性寄生虫感染症で,約800万人の人に感染しています.
- 感染した人の有意な部分 (30-40%) は,心筋病や消化器系の問題などの重篤な合併症を発症します.
- 近年,シャガス病の制御に進展がみられるが,非流行地域での出現を含む課題は依然として残っている.
研究 の 目的:
- シャガス病の管理と制御における最近の進歩をレビューする.
- 持続的な課題と将来の研究と介入の分野を強調する.
主な方法:
- 疫学的データと制御プログラムの結果のレビュー.
- 現在の治療戦略とリスクの階層化モデルの分析.
- チャガス病管理における新興傾向と満たされていないニーズについての議論.
主要な成果:
- ベクター制御と献血者のスクリーニングは,シャガス病の発生率と流行を成功裏に減少させました.
- ベンズニダゾールやニフュルティモックスなどの現在の治療法は有効で,より広い患者グループに推奨されています.
- 改善されたリスク分層化モデルは,潜在的に疾患の進行を停止したり逆転させたりするための治療をガイドするのに役立ちます.
結論:
- 予防対策は改善されていますが,特に人口の移動により,シャガス病は依然として重要な公衆衛生上の懸念となっています.
- 症状のない症例の早期発見と治療は十分に活用されていない.
- 新しい治療法を評価し,シャガス病の世界的な蔓延に対処するためにさらなる研究が必要です.
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