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Updated: May 11, 2026

Using Next Generation Sequencing to Identify Mutations Associated with Repair of a CAS9-induced Double Strand Break Near the CD4 Promoter
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Using Next Generation Sequencing to Identify Mutations Associated with Repair of a CAS9-induced Double Strand Break Near the CD4 Promoter

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RAD6のDNAダメージ耐性経路は,複製フォークから切り離されて動作し,S相を超えて機能しています

Georgios I Karras1, Stefan Jentsch

  • 1Department of Molecular Cell Biology, Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany.

Cell
|April 21, 2010
PubMed
まとめ

DNAダメージ耐性経路であるRAD6とトランスレション合成 (TLS) は,S段階だけでなくG2/M段階でも効果的に機能します. これは,複製が再開された後,単一鎖のギャップに作用することを示唆しています.

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Analysis of Nonhomologous End Joining and Homologous Recombination Efficiency in HEK-293T Cells Using GFP-Based Reporter Systems09:29

Analysis of Nonhomologous End Joining and Homologous Recombination Efficiency in HEK-293T Cells Using GFP-Based Reporter Systems

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