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Updated: Jun 13, 2026

Artificial RNA Polymerase II Elongation Complexes for Dissecting Co-transcriptional RNA Processing Events
10:59

Artificial RNA Polymerase II Elongation Complexes for Dissecting Co-transcriptional RNA Processing Events

Published on: May 13, 2019

翻訳リボソームとRNAポリメラーゼの間の協力は,転写の延長における協力である

Sergey Proshkin1, A Rachid Rahmouni, Alexander Mironov

  • 1Department of Biochemistry, New York University School of Medicine, New York, NY 10016, USA.

Science (New York, N.Y.)
|April 24, 2010
PubMed
まとめ

バクテリアの翻訳速度は,RNAポリメラーゼ (RNAP) の延長に影響することによって,転写速度を直接制御する. リボソームはRNAPの逆行を防止し,遺伝子発現を細胞のニーズと調整する.

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Transcription Elongation Factors02:35

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Transcription Elongation Factors02:35

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Transcription elongation is a dynamic process that alters depending upon the sequence heterogeneity of the DNA being transcribed. Hence, it is not surprising that the elongation complex's composition also varies along the way while transcribing a gene.
The transcription elongation is regulated via pausing of RNA polymerase on several occasions during transcription. In bacteria, these halts are necessary because the transcription of DNA into mRNA is coupled to the translation of that mRNA into a...
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