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Updated: Jun 13, 2026

Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes
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チオペプチド抗生物質に対する微生物耐性の分子決定因子

Sascha Baumann1, Sebastian Schoof, Marcel Bolten

  • 1Fakultat Chemie, Technische Universität Dortmund, Otto-Hahn-Strasse 6, D-44221 Dortmund, Germany.

Journal of the American Chemical Society
|May 6, 2010
PubMed
まとめ

チオペプチド抗生物質は,細菌のリボソームを標的とする. リボソームRNA (rRNA) の突然変異は結合に影響し,リボソームタンパク質L11の突然変異は,タンパク質合成の阻害をバイパスすることで,バイサイクルチオペプチドに対する耐性を授与する.

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