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Updated: May 1, 2026

Fluorescence-based Monitoring of PAD4 Activity via a Pro-fluorescence Substrate Analog
08:37

Fluorescence-based Monitoring of PAD4 Activity via a Pro-fluorescence Substrate Analog

Published on: November 5, 2014

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PtdIns(3,4)P(2) フォスファタゼINPP4Aは,興奮毒性ニューロン死亡の抑制剤である

Junko Sasaki1, Satoshi Kofuji, Reietsu Itoh

  • 1Department of Medical Biology, Akita University Graduate School of Medicine, Akita 010-8543, Japan. sasakij@med.akita-u.ac.jp

Nature
|May 14, 2010
PubMed
まとめ

イノシトールポリフォスファート・フォスファタゼ4A (INPP4A) は,脳におけるグルタミン酸興奮毒性を抑制する. INPP4Aの喪失は,神経変性および運動障害を引き起こし,神経細胞の保護と潜在的な治療戦略におけるその役割を強調します.

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