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Updated: Jun 13, 2026

Quantitative Determination of De Novo Fatty Acid Synthesis in Brown Adipose Tissue Using Deuterium Oxide
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マイクロRNA-33とSREBPの宿主遺伝子は,コレステロールのホメオスタシスを制御するために協力します

S Hani Najafi-Shoushtari1, Fjoralba Kristo, Yingxia Li

  • 1Massachusetts General Hospital Cancer Center, Charlestown, MA 02129, USA.

Science (New York, N.Y.)
|May 15, 2010
PubMed
まとめ

マイクロRNA (miR-33a/b) は,ABCA1.1を標的にしてコレステロールのホメオスタシスを調節する. miR-33を阻害すると,HDL合成とコレステロール流出が増加し,miR-33が心臓代謝疾患の治療標的であることを示唆しています.

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