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Updated: Jun 12, 2026

Method to Visualize and Analyze Membrane Interacting Proteins by Transmission Electron Microscopy
10:49

Method to Visualize and Analyze Membrane Interacting Proteins by Transmission Electron Microscopy

Published on: March 5, 2017

膜-水界面での分子認識:膜外核塩基ペアリングによる統合ペプチドヘリクスの制御

Philipp Erik Schneggenburger1, Stefan Müllar, Brigitte Worbs

  • 1Institute for Organic and Biomolecular Chemistry, Georg-August-University Göttingen, 37077 Göttingen, Germany.

Journal of the American Chemical Society
|May 21, 2010
PubMed
まとめ

研究者らは,ペプチド核酸 (PNA) による新型トランスメブランペプチドを設計し,その結合を制御した. この研究は,これらのペプチドモデルシステムを用いて膜タンパク質の組立と機能を研究するための新しい方法を示しています.

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Multi-pass Transmembrane Proteins and β-barrels

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α-Helix containing multi-pass transmembrane proteins
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Protein-protein Interfaces

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Plasma membranes have integral transmembrane proteins involved in facilitated transport. These proteins are collectively referred to as transport proteins, and they function as either channels for the material or as carriers themselves. Channel proteins have hydrophilic domains exposed to the intracellular and extracellular fluids and a hydrophilic channel through their core that provides a hydrated opening for solutes to pass through the membrane layers. Passage through the channel allows...