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Updated: May 26, 2026

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells
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TLR/IL-1RシグナリングにおけるMyD88-IRAK4-IRAK2複合体の螺旋組

Su-Chang Lin1, Yu-Chih Lo, Hao Wu

  • 1Department of Biochemistry, Weill Cornell Medical College, New York, New York 10021, USA.

Nature
|May 21, 2010
PubMed
まとめ

MyD88-IRAK4-IRAK2死の領域複合体は,ユニークな螺旋構造を形成し,Tollのような受容体シグナリングがどのように開始されるかを明らかにします. この発見は,重要なシグナル伝達経路の組み立てと規制を明確にします.

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