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Updated: May 3, 2026

The c-FOS Protein Immunohistological Detection: A Useful Tool As a Marker of Central Pathways Involved in Specific Physiological Responses In Vivo and Ex Vivo
05:44

The c-FOS Protein Immunohistological Detection: A Useful Tool As a Marker of Central Pathways Involved in Specific Physiological Responses In Vivo and Ex Vivo

Published on: April 25, 2016

33.6K

リガンド特異のc-Fos発現は,ErbBネットワークダイナミクスの空間時間的な制御から生じる

Takashi Nakakuki1, Marc R Birtwistle, Yuko Saeki

  • 1Computational Systems Biology Research Group, Advanced Computational Sciences Department, RIKEN Advanced Science Institute, 1-7-22 Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan.

Cell
|May 25, 2010
PubMed
まとめ

皮膚表皮成長因子 (EGF) とヘレグルリン (HRG) は,共有された経路を通じて異なる細胞運命を誘発する. 数学的モデリングは,これらのリガンドがERK信号ダイナミクスを制御することによって,ユニークなc-Fos応答を生成する方法を示しています.

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