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Updated: Jun 12, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
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A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products

Published on: October 4, 2019

エンゲリンのAAの総合成

K C Nicolaou1, Qiang Kang, Sin Yee Ng

  • 1Chemical Synthesis Laboratory@Biopolis, Institute of Chemical and Engineering Sciences (ICES), Agency for Science, Technology and Research (A*STAR), 11 Biopolis Way, The Helios Block, #03-08, Singapore 138667. kcn@scripps.edu

Journal of the American Chemical Society
|May 26, 2010
PubMed
まとめ

研究者は,腎臓がん細胞の成長を抑制する強力な化合物であるエンゲリンAの全合成を達成しました. この突破は,重要な [5 + 2] サイクル添加反応を利用し,さらなる構造-活性関係研究への道を開いた.

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