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Updated: Jun 12, 2026

Single-Cell Calcium Imaging for Studying the Activation of Calcium Ion Channels
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Single-Cell Calcium Imaging for Studying the Activation of Calcium Ion Channels

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双価なタランチュラ毒素は,外部の毛穴領域をターゲットにすることで,カプサイシン受容体TRPV1を活性化させます

Christopher J Bohlen1, Avi Priel, Sharleen Zhou

  • 1Department of Physiology, University of California, San Francisco, San Francisco, CA 94143-2140, USA.

Cell
|June 1, 2010
PubMed
まとめ

新しいタランチュラ毒素である"ダブルノット"ペプチドは,TRPV1チャネルを不可逆的に活性化します. そのユニークな二価構造は,TRPチャネル活性化における外孔構造の変化の役割を強調しています.

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