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Updated: May 9, 2026

Monitoring Cleaved Caspase-3 Activity and Apoptosis of Immortalized Oligodendroglial Cells using Live-cell Imaging and Cleaveable Fluorogenic-dye Substrates Following Potassium-induced Membrane Depolarization
10:45

Monitoring Cleaved Caspase-3 Activity and Apoptosis of Immortalized Oligodendroglial Cells using Live-cell Imaging and Cleaveable Fluorogenic-dye Substrates Following Potassium-induced Membrane Depolarization

Published on: January 13, 2012

ミトコンドリア経由のカスパース-3活性化は,長期的なうつ病およびAMPA受容体の内部化のために必要である

Zheng Li1, Jihoon Jo, Jie-Min Jia

  • 1The Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. lizheng2@mail.nih.gov

Cell
|June 1, 2010
PubMed
まとめ

ミトコンドリアのカスパース-3の活性化は,長期うつ病 (LTD) とニューロン内のAMPA受容体除去に不可欠です. このアポトーシス経路は,細胞死を引き起こすことなく,シナプス性可塑性にとって不可欠です.

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A High-content Assay for Monitoring AMPA Receptor Trafficking10:34

A High-content Assay for Monitoring AMPA Receptor Trafficking

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