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Updated: Jun 12, 2026

Computational Prediction of Amino Acid Preferences of Potentially Multispecific Peptide-Binding Domains Involved in Protein-Protein Interactions
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Computational Prediction of Amino Acid Preferences of Potentially Multispecific Peptide-Binding Domains Involved in Protein-Protein Interactions

Published on: January 26, 2024

テンプレートタンパク質インターフェースにおける金属選択性の進化

Jeffrey D Brodin1, Annette Medina-Morales, Thomas Ni

  • 1Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California 92093-0356, USA.

Journal of the American Chemical Society
|June 3, 2010
PubMed
まとめ

研究者らは,亜鉛イオンを選択的に結合するタンパク質アセンブリ (C96) RIDC-1 ((4) を設計した. この金属テンプレートの再設計は,特定の金属結合機能を持つメタロタンパク質を作成するための新しい戦略を示しています.

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