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Updated: Jun 12, 2026

Nanomanipulation of Single RNA Molecules by Optical Tweezers
06:59

Nanomanipulation of Single RNA Molecules by Optical Tweezers

Published on: August 20, 2014

分子混雑は,排除された体積効果によって折りたたまれたRNA構造を安定させる

Duncan Kilburn1, Joon Ho Roh, Liang Guo

  • 1T. C. Jenkins Department of Biophysics, Johns Hopkins University, Baltimore, Maryland 21218, USA.

Journal of the American Chemical Society
|June 5, 2010
PubMed
まとめ

ポリエチレングリコール (PEG) の分子混雑は,溶液の均衡を変化させることで,コンパクトなRNA構造を好みます. この研究は,PEG-1000が細菌のリボエンザイムによりコンパクトな状態を誘導し,折り畳みの熱力学に影響を与えることを示しています.

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