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Updated: Jun 12, 2026

Yeast As a Chassis for Developing Functional Assays to Study Human P53
14:57

Yeast As a Chassis for Developing Functional Assays to Study Human P53

Published on: August 4, 2019

メイオティック再結合は,p53 調節ネットワークの機能的活性化を誘発する

Wan-Jin Lu1, Joseph Chapo, Ignasi Roig

  • 1Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Science (New York, N.Y.)
|June 5, 2010
PubMed
まとめ

p53タンパク質ネットワークは,DNA修復を含む保存されたプロセスであるメオシス中に活性化されます. この発見は,p53の生理学的役割が腫瘍抑制を超えて,遺伝的再結合に関連していることを明らかにしています.

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