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Updated: Jun 12, 2026

Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR
14:44

Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR

Published on: December 16, 2013

部分折りたたまれたタンパク質の構造アンサンブルを評価するための組み合わせのNMRとEPRアプローチ

Jampani Nageswara Rao1, Christine C Jao, Balachandra G Hegde

  • 1Department of Biochemistry & Molecular Biology, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, 1501 San Pablo Street, Los Angeles, California 90033, USA.

Journal of the American Chemical Society
|June 8, 2010
PubMed
まとめ

この研究では,アルファ-シヌクレインのような部分折りたたまれたタンパク質を分析するために,EPRとNMRを組み合わせた新しい方法が導入されています. 詳細なタンパク質-ミセル相互作用を明らかにし,ヘリックスダイナミクスがミセル構造の変化にどのように関係しているかを示しています.

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