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Updated: Jun 12, 2026

Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues
12:07

Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues

Published on: November 22, 2014

タンパク質-コファクター相互作用のプローブとしてコファクターメチル群の阻害された回転

Richard Brosi1, Boris Illarionov, Tilo Mathes

  • 1Fachbereich Physik, Institut für Experimentalphysik, Freie Universität Berlin, Arnimallee 14, 14195 Berlin, Germany.

Journal of the American Chemical Society
|June 12, 2010
PubMed
まとめ

低温ENDORスペクトロスコピーは,LOVドメインにおけるフラビンモノヌクレオチド (FMN) メチル群の回転を分析することによって,タンパク質-コファクター相互作用を明らかにします. この方法は,分子詳細を正確に探査し,光受容体の機能に影響を与えるAsn425のような重要なアミノ酸を特定します.

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