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Updated: Jun 12, 2026

In Vitro Directed Evolution of a Restriction Endonuclease with More Stringent Specificity
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Published on: March 25, 2020

PNA酵素は人工的なRNA制限酵素である

Merita Murtola1, Malgorzata Wenska, Roger Strömberg

  • 1Department of Biosciences and Nutrition, Karolinska Institutet, Novum, S-14183, Huddinge, Sweden.

Journal of the American Chemical Society
|June 16, 2010
PubMed
まとめ

研究者らは,ペプチド核酸を用いた人工酵素である新しいPNAzymesを開発し,シーケンス固有のRNasesとして作用した. これらのPNA酵素は,精密な部位でRNAを効率的に分割し,バイオテクノロジーのアプリケーションのための自然な制限酵素を模倣します.

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Ribozymes02:47

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