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Updated: May 5, 2026

Antibody Binding Specificity for Kappa (Vκ) Light Chain-containing Human (IgM) Antibodies: Polysialic Acid (PSA) Attached to NCAM as a Case Study
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Antibody Binding Specificity for Kappa (Vκ) Light Chain-containing Human (IgM) Antibodies: Polysialic Acid (PSA) Attached to NCAM as a Case Study

Published on: June 29, 2016

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シアリック酸アセチルエステラーゼの機能的に欠陥のある生殖系変種は,自己免疫において

Ira Surolia1, Stephan P Pirnie, Vasant Chellappa

  • 1Cancer Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA.

Nature
|June 18, 2010
PubMed
まとめ

シアリック酸アセチルエステラーゼ (SIAE) の欠陥変種は,自己免疫疾患と強く関連しています. これらのSIAE遺伝子欠陥は,リウマチ性関節炎や1型糖尿病などの疾患を発症するリスクを高めます.

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Metabolic Glycoengineering of Sialic Acid Using N-acyl-modified Mannosamines

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Author Spotlight: Dendritic Cells Maturation Using Sialidases-Based Enzymatic Treatment of the Cell Surface

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