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Updated: Jun 12, 2026

Purification and Quality Control of Recombinant Septin Complexes for Cell-Free Reconstitution
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Purification and Quality Control of Recombinant Septin Complexes for Cell-Free Reconstitution

Published on: June 23, 2022

主の底にあるセプチン拡散障壁は,膜タンパク質の分布を維持する

Qicong Hu1, Ljiljana Milenkovic, Hua Jin

  • 1Department of Biology, Stanford University, Stanford, CA 94305, USA.

Science (New York, N.Y.)
|June 19, 2010
PubMed
まとめ

セプチン2 (SEPT2) は,プライマリシリウム底部で拡散障壁を形成し,シグナル伝達タンパク質を保持します. SEPT2の枯渇は信号伝達とシリオゲネシスを妨害し,シリヤ機能における重要な役割を強調します.

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Bottom-Up In Vitro Methods to Assay the Ultrastructural Organization, Membrane Reshaping, and Curvature Sensitivity Behavior of Septins09:09

Bottom-Up In Vitro Methods to Assay the Ultrastructural Organization, Membrane Reshaping, and Curvature Sensitivity Behavior of Septins

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Role of Septins01:02

Role of Septins

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Cellular Functions of Septins
Recent studies have revealed the multifaceted roles of septins in various cellular processes such as cytokinesis, ciliogenesis, and neurogenesis. Septins act as scaffolds and...
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Septins

Septins are protein filaments forming the cytoskeleton along with the microtubules, microfilaments, intermediate filaments, and other accessory proteins. In 1971 while studying the cell division cycle in mutant Saccharomyces cerevisiae Harwell et al. first identified the septin-related genes playing a crucial role in yeast cytokinesis. Fluorescence microscopy revealed that these proteins localize at the budding neck as rings. These ring-like proteins were then named Septins by John Pringle, and...
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Mechanism of Ciliary Motion

The ciliary structures were first seen in 1647 by Antonie Leeuwenhoek while observing the protozoans. In lower organisms, these appendages are responsible for cell movement, while in higher organisms, these appendages help in the movement of the extracellular fluids within the body cavities.
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