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Updated: Jun 12, 2026

MicroRNA-based Regulation of Picornavirus Tropism
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MicroRNA-based Regulation of Picornavirus Tropism

Published on: February 6, 2017

ヘルペスウイルスの非コーディングRNAによる宿主マイクロRNAのダウン調節

Demián Cazalla1, Therese Yario, Joan A Steitz

  • 1Department of Molecular Biophysics and Biochemistry, Howard Hughes Medical Institute, Yale University School of Medicine, Boyer Center for Molecular Medicine, 295 Congress Avenue, New Haven, CT 06536, USA.

Science (New York, N.Y.)
|June 19, 2010
PubMed
まとめ

ヘルペスウイルスサイミリは,ウイルスのノンコーディングRNA (HSUR) を使用してT細胞を変容させ,宿主マイクロRNA (miRNA) を分解します. このウイルスの戦略は,HSUR 1 が,miRNA経路を通じて宿主遺伝子の発現を操作する方法を示しています.

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