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依存症への移行は,シナプス可塑性の持続的な障害と関連しています

Fernando Kasanetz1, Véronique Deroche-Gamonet, Nadège Berson

  • 1INSERM U862, NeuroCentre Magendie, 147 Rue Léo Saignat, 33077, Bordeaux Cedex, France.

Science (New York, N.Y.)
|June 26, 2010
PubMed
まとめ

慢性的な薬物曝露は,脳の機能を変化させます. 依存症は,重要なシナプス可塑性メカニズムであるアキュンベンス核の長期的なうつ病 (LTD) と関連しており,制御された摂取は回復を可能にします.

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