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早期のT細胞系統のコミットメントチェックポイントは,転写因子Bcl11bbに依存する

Long Li1, Mark Leid, Ellen V Rothenberg

  • 1Division of Biology 156-29, California Institute of Technology, Pasadena, CA 91125, USA.

Science (New York, N.Y.)
|July 3, 2010
PubMed
まとめ

亜鉛指の転写因子Bcl11bは,Tリンパ球の系統のコミットメントに不可欠です. この転写因子は,自然殺人細胞の潜在能力を抑制し,T細胞発達の過程で幹細胞遺伝子を静止するために不可欠です.

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