フリッピングMLL1のスイッチは,プロリンを1つずつスイッチします
Edward J Grow1, Joanna Wysocka
1Department of Genetics, Stanford University, Stanford, CA 94305, USA.
Cell
|July 7, 2010
まとめ
混合系白血病1 (MLL1) タンパク質は,血液の発達におけるホックス遺伝子を調節する. サイクロフィリンCyP33と呼ばれるタンパク質は,MLL1をスイッチします.
科学分野:
- 分子生物学は分子生物学である.
- ヘマトポエーシス (血液形成) とは
- エピジェネティクス エピジェネティクス
背景:
- 混合系白血病1 (MLL1) タンパク質は,血液形成中のホックス遺伝子発現を調節する上で重要な役割を果たします.
- MLL1の障害は,様々なタイプの白血病で頻繁に観察されます.
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