タンパク質の折りたたみで動力的に閉じ込められた状態のチャペロニン触媒による救出

Kausik Chakraborty1, Manal Chatila, Jyoti Sinha

  • 1Department of Cellular Biochemistry, Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany.

Cell
|July 7, 2010
PubMed
まとめ

GroEL/GroESのようなチャペロニンケージは,タンパク質が誤った折り畳み状態に引っかかることを防ぐことで,タンパク質の折り畳みに役立ちます. この研究は,これらの"折りたたみ罠"を形成する傾向にあるタンパク質が,チャペロニンの援助から最も恩恵を受けることを示しています.

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