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Updated: Jun 11, 2026

The Determination of Protease Specificity in Mouse Tissue Extracts by MALDI-TOF Mass Spectrometry: Manipulating PH to Cause Specificity Changes
09:47

The Determination of Protease Specificity in Mouse Tissue Extracts by MALDI-TOF Mass Spectrometry: Manipulating PH to Cause Specificity Changes

Published on: May 25, 2018

脊椎の柔軟性は,タンパク質-タンパク質インターフェースの活性と特異性を制御する:ヘビの毒の金属プロテアゼにおける特異性

Hannes G Wallnoefer1, Torsten Lingott, José María Gutiérrez

  • 1Institute of General, Inorganic and Theoretical Chemistry, Faculty of Chemistry and Pharmacy, University of Innsbruck, Innrain 52a, A-6020 Innsbruck, Austria.

Journal of the American Chemical Society
|July 13, 2010
PubMed
まとめ

蛇の毒メタロプロテアゼ (SVMPs) は,タンパク質の柔軟性の違いにより,さまざまな出血活動を示す. コンピューターシミュレーションにより,SVMPの特定のループダイナミクスは,基礎膜タンパク質を結合し,分解し,出血を引き起こす能力を決定していることが明らかになりました.

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Production, Crystallization, and Structure Determination of the IKK-binding Domain of NEMO13:02

Production, Crystallization, and Structure Determination of the IKK-binding Domain of NEMO

Published on: December 28, 2019

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