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Updated: Jun 10, 2026

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シグナリングキナーゼAMPKは,ヒストンH2Bのリン酸化経由でストレス誘発による転写を活性化させます

David Bungard1, Benjamin J Fuerth, Ping-Yao Zeng

  • 1Department of Cellular and Developmental Biology, University of Pennsylvania Medical School, Philadelphia, PA 19104, USA.

Science (New York, N.Y.)
|July 22, 2010
PubMed
まとめ

アデノシンモノフォスファート活性化タンパク質キナーゼ (AMPK) は細胞のエネルギーを調節する. この研究は,AMPKがヒストンH2Bをセルリン36で直接リン酸化し,ストレス適応のための遺伝子転写を活性化することを明らかにしています.

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