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Updated: Jun 10, 2026

Rab10 Phosphorylation Detection by LRRK2 Activity Using SDS-PAGE with a Phosphate-binding Tag
08:55

Rab10 Phosphorylation Detection by LRRK2 Activity Using SDS-PAGE with a Phosphate-binding Tag

Published on: December 14, 2017

レジオネラエフェクタータンパク質DrrA AMPは,膜のトラフィックレギュレータRab1bbをフィラットする

Matthias P Müller1, Heide Peters, Julia Blümer

  • 1Department of Physical Biochemistry, Max Planck Institute of Molecular Physiology, Dortmund, NRW, 44227, Germany.

Science (New York, N.Y.)
|July 24, 2010
PubMed
まとめ

レジオネラ肺炎菌は,DrrAタンパク質を使用して,小さなGTPaseであるAMPylate (一種の改変) Rab1bにAMPylate (一種の改変) をします. この改変により,Rab1bは活性状態に閉じられ,レジオネアーズの間に細胞の取引が妨げられます.

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Applying Live Cell Imaging and Cryo-Electron Tomography to Resolve Spatiotemporal Features of the Legionella pneumophila Dot/Icm Secretion System

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