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Updated: Jun 10, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
10:17

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

スピロインドレーニンのエナチオセレクティブ構築は,Ir-触媒化されたアリルアルキル化反応によって行われます

Qing-Feng Wu1, Hu He, Wen-Bo Liu

  • 1State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, China.

Journal of the American Chemical Society
|August 4, 2010
PubMed
まとめ

新しいイリジウム触媒反応により,インドールからエナチオ濃縮されたスパイロインドレーニン誘導体の合成が可能になる. この方法は,ユニークなフォスフォラミミド酸リガンドを使用して,高収量と優れたステレオ選択性を達成します.

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