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Updated: Jun 10, 2026

Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine
09:14

Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine

Published on: February 16, 2018

ステレオ化学的に互補的な生体触媒を生成するために,ステレオ化学的に不規則なアルドラーゼの構造的に知られたサイト誘導性変異を生成する

Sylvain F Royer1, Luke Haslett, Susan J Crennell

  • 1Centre for Extremophile Research, Department of Biology and Biochemistry, University of Bath, Bath, United Kingdom BA2 7AY.

Journal of the American Chemical Society
|August 6, 2010
PubMed
まとめ

研究者は,炭素-炭素結合形成におけるステレオ化学的制御を改善するために,Sulfolobus solfataricusから熱安定性アルドラーゼ酵素を設計しました. この作業により,特定のD-2-ケト-3-デオキシグルコナート (D-KDGlu) とD-2-ケト-3-デオキシガラクトナート (D-KDGal) のイソメアの生成が強化されます.

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Directed Evolution Method in Saccharomyces cerevisiae: Mutant Library Creation and Screening

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Site-Directed Mutagenesis for In Vitro and In Vivo Experiments Exemplified with RNA Interactions in Escherichia Coli07:04

Site-Directed Mutagenesis for In Vitro and In Vivo Experiments Exemplified with RNA Interactions in Escherichia Coli

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