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Updated: Jun 10, 2026

In Vitro Assay for Studying the Aggregation of Tau Protein and Drug Screening
09:49

In Vitro Assay for Studying the Aggregation of Tau Protein and Drug Screening

Published on: November 20, 2018

本質的に無秩序なタンパク質であるタウを441残基で自動的に代入する

Rhagavendran L Narayanan1, Ulrich H N Dürr, Stefan Bibow

  • 1Department of NMR-based Structural Biology, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Goettingen, Germany.

Journal of the American Chemical Society
|August 7, 2010
PubMed
まとめ

タウのような本質的に乱れたタンパク質を特徴づけるのは,信号が重なり合うために困難です. この研究は,高度なNMR方法を使用してタウタンパク質の構造と動態を効率的に割り当て,グローバルな折り畳みの証拠を明らかにしました.

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