フェノールから3トリフルオロメチルベンゾ[b]フランを,拡張プメラー反応による直接オーソ機能化経由で合成する

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Updated: Jun 10, 2026

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
08:43

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives

Published on: January 19, 2016

Takayuki Kobatake1, Daishi Fujino, Suguru Yoshida

  • 1Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyoto-daigaku Katsura, Nishikyo-ku, Kyoto 615-8510, Japan.

Journal of the American Chemical Society
|August 7, 2010
PubMed
まとめ

新しい方法は,フェノールからトリフルオロメチルベンゾ[b]フランを効率的に合成する. このアプローチは,トリフリックアンヒドリド媒介のプマーラー反応を利用し,その後のメチルチオ群の改変によって多様な製品形成を可能にします.

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Application of Elemental Lanthanides in the Selective C-F Activation of Trifluoromethylated Benzofulvenes Providing Access to Various Difluoroalkenes

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Efficient Synthesis of Polyfunctionalized Benzenes in Water via Persulfate-promoted Benzannulation of α,β-Unsaturated Compounds and Alkynes05:34

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