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Updated: Jun 10, 2026

In-vitro Reconstitution of Bacterial Ubiquitination and VCP/p97-mediated Elimination
07:58

In-vitro Reconstitution of Bacterial Ubiquitination and VCP/p97-mediated Elimination

Published on: January 2, 2026

グルタミンデアミデーションとウビキチン/NEDD8の機能障害は,バクテリアのエフェクターファミリーによって誘発される

Jixin Cui1, Qing Yao, Shan Li

  • 1Graduate Program in Chinese Academy of Medical Sciences and Beijing Union Medical College, Beijing 100730, China.

Science (New York, N.Y.)
|August 7, 2010
PubMed
まとめ

バクテリアのタンパク質CHBPとCifは,ウビキチンとNEDD8.8をデアミダ化することによって,ウビキチン化経路を阻害する. このデアミデーションは,ユビキチン鎖合成とCRLリガゼ活性を損なっており,細胞サイクルとアクチン構造に影響を与えます.

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Monitoring of Ubiquitin-proteasome Activity in Living Cells Using a Degron (dgn)-destabilized Green Fluorescent Protein (GFP)-based Reporter Protein10:25

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Published on: November 10, 2012

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