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Updated: Jun 10, 2026

Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels
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Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels

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ホモジマータンパク質構造の決定のためのNMRとEPRの組み合わせによる方法

Yunhuang Yang1, Theresa A Ramelot, Robert M McCarrick

  • 1Department of Chemistry and Biochemistry, Miami University, Oxford, Ohio 45056, USA.

Journal of the American Chemical Society
|August 12, 2010
PubMed
まとめ

この研究は,タンパク質の複合構造を決定するために,パラマグネティック・リラクゼーション・エンハンスメント (PRE) とダブル電子電子共振 (DEER) と核磁気共振 (NMR) を統合しています. この組み合わせのアプローチは,大型分子の場合でも,ホモジマー構造を正確に定義します.

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